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The (rnrs mutable-strings (6)) library provides the 
string-set! and string-fill! procedures, which allow the
content of strings to be modified “in-place.”
These procedures are identical to the ones provided by Guile’s core
library.  See String Modification, for documentation.  All strings in
Guile are mutable; consequently, these procedures will never throw the 
&assertion condition described in the R6RS libraries 
specification.